Kemba Walker had 18 points, Jaylen Brown 17, Daniel Theis 13 and Robert Williams III 10 as the Celtics won their fifth straight game to open the playoffs. Theis and Walker added game highs of 15 rebounds and 10 assists, respectively.
Kyle Lowry had 17 points and Serge Ibaka added 15 for the Raptors, who saw their eight-game winning streak come to a halt.
Toronto shot 31-of-84 (36.9 per cent) from the field and 10-of-40 (25.0 per cent) from three-point range. Pascal Siakam and Fred VanVleet combined to go 8-of-32 for 24 points.
Game 1 of the seven-game series had originally been scheduled for Thursday before player protests related to the police shooting of Jacob Blake in Wisconsin pushed back the NBA schedule.
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